While there may not be the marquee game on the schedule for college football's Week 4, there are plenty of games that will shift the College Football Playoff and conference championship picture. It's a weird week when College Gameday is in Times Square and the Saturday Night. With so many eye-popping games and so many college football odds on the move, you'll want to know why the "sharps" are picking against the. The 21 best bets for Week 4 college football, including *defense* in Visit Odds Shark for updated lines throughout each game week. Season.